Duck hunting in ND Essay Example for Free

Duck laming in ND Es enounceBOOM Then, dead silence. The water ripples as the smell of gunman powder fills the air. The victim is seen bewildered by the going watch. Now if this is what sounds like a thrill to you, bury catch is the way to go. If round(prenominal)one were to ask me what my favorite hobby is, I would have to speculate duck hunting in North Dakota. Some may not consider it a hobby because I only duck hunt quaternity days a year, but I still do. I also duck hunt behind our house on Trident Lake another three to ten-spot days a year. Duck hunting is very different from other types of hunting.Usu tout ensembley hunters have to be still and quiet when deer and turkey hunting. When duck hunting, a necessity is to keep the eyes down. It doesnt matter if talking or moving is involved, as long as the duck pilet see the hunters eyes. The process of preparing to go duck hunting is quite tedious. A hunter must pack thoroughly, not just the fair cooking utensils but also duck calls, blinds, seats, clothes, food, a trailer, decoys, guns, and over often more. I usually prep ar for North Dakota a week early, because I feel so excited, which gives me more judgment of conviction to become prep ard.Usually I go with my dad and my sister, but the year I am going on the man journey with my dad and uncle. It will be more fun in my eyes, because I am with more experienced hunters, and that makes the trip easier. People might be question why I need all these decoys and duck calls. They ar quick to learn once I tell them. When hunting for ducks around Polk County, Wisconsin, there are deuce main type of ducks, Mallards and Wood ducks. Occasionally there will be a Buffle Head or two, but not very often. In Verona, North Dakota, there are many ducks my dad and I charge.These ducks are that my dad and I shoot are Pintails, Shovelers, Mallards, Northern Mallards, Widgeon, Red Heads, Blue Bills, Buffle Head, Gadwall, mobilize Necks, Coots, Canvasbac ks, Diver Ducks, Green Wing Teal, Blue Wing Teal, and Hooded Mergansers. If people think sixteen is much, just remember that there is a female to every male. Its very interesting to hunt ducks in North Dakota. Its not like anyone can just travel out of state and hunt ducks. To hunt in North Dakota, it requires and out-of-state license and knowledge of the daily bag limit for each type of duck.Some ducks are what hunters call, banded which means the Federal slant and Game Wildlife Service set ups a metal ring around the ducks foot. After that duck is snap fastener, the Federal Fish and Game Wildlife Service can tell the hunter where the duck was banded. Then a free picture frame with the certificate of authentication will be sent to the hunters home. Its an amazing experience for close toone like me who has been hunting for three geezerhood to shoot a banded duck. My dad has been hunting for 15 years and has only shot one.Now with a general lowstanding of what its like to be a duck hunter, I will go into some more in-depth daily routines. When traveling to go hunting, my dad and I usually wake up at about 530 in the morning. at one time we are dressed for the, 0-45 degree Fahrenheit temperature, we can pack up and leave. Generally scouting for a hunting spot is done by hot hunters a day in advance. This process can take anywhere from one to six hours. To find the perfect pothole, also known as freshwater marshes found in the Upper Midwest and especially North Dakota, just look for where the ducks are landing and set up in that spot the next morning.Once we travel to the pothole, we find a perspective in the cattails reeds or on land to put our guns, ammunition bag, buckets to sit on and miscellaneous items. Decoys are then set out strategically according to the wind and what type of ducks we are hunting for. Now all the preparation is put into be activeion, as the hunting begins. Imagine sitting in the middle of the pothole at 645 in the morning, wi th ducks disappearing unknowingly to the water surrounded by two armed hunters. Imagine seeing the sunrise above the wind breakers, made of trees, a beautiful orange and red glow.Imagine hearing coyotes howling all around the water, as the hunter patiently waits for the shooting hour to arrive. Then the clock hits 715, just as the sky is visible enough to see. Ducks are flying all around, with their wings cupped and ready to land into the wind at your direction. The first shot burst out, as an echo is heard in the distance, loss a glowing red out of the end of the 12 gauges barrel. Smoke fills the air, and its time to wake up and have some fun When ducks are flying in the sky, they fly in a V shape and land into the wind.The cattail reeds around are five to eight feet towering and are broken down to be used as a gun rest and as a shooting lane. Ducks are flying in as the hunter stars the female Mallard comeback call, to bring the drakes and hen Mallards in. The ducks lands in the pothole with wings cupped and the perfect time to pull a gun up as a hunter is right before the ducks bring their feet out to land. Once this is achieved by the hunter the ducks are defenseless, not knowing whether to fly up or just land in the water. Its almost as if the ducks are levitating in air. As a hunter, this is the prime time to shoot at the ducks.Once the duck is hit, preferably in the head or torso, it hits the water causing a rippling effect. Diver Ducks try to dive under once hit, and drown the-selves in the weeds. Most other ducks do the circle of death, where a duck flaps its wings around in a circle on the water, just before dying. Understand this, there is something that is different about killing ducks than other animals. When a duck is flying 30 miles per hour in the air, they are pretty hard to hit. But when a deer is standing still, it feels too easy to shoot. As a hunter, I take some self-pride in killing a duck, almost as if I achieved something by hitting it.Therefore, anyone else reading this that duck hunts should to. A lesson learning incident took place while duck hunting one time. I was looking to the left for ducks in the air and before I knew, there was a duck school principal straight for my face. As I turned right I saw the duck five feet from my face, the feeling cant even be put into words Many may not believe me, but when that duck flew by my head, it literally sounded like a jet taking off. Im not sure if it has to do with the wing structure on the duck, or air current resulting in the extremely loud sound. This just goes to show, that every hunter has to stay alert.Duck hunting is full of surprises, for the good and bad. When taking a shot at just one duck or a flock, it is precise to make sure that the ducks is in range. Most hunters typically say no more than 30 yards away. Range for shooting a duck all has to do with how a hunter has his BB pattern laid out. The spread on a shotgun is set wide for smaller distances and more BB spread, and tight for farther shot and less BB spread. Another reason why a hunter should take caution when shoot is because, ammunition is very expensive. A box of Black cloud 12 Gauge 3in 1 1/4oz shells, which are great to hunt with, hail $20. 49 for a box of 25 shells.Another way to say it is, shooting a dollar out of the barrel every shot. For me and I imagine other hunter, when its all in fun for the love of the sport, cost doesnt really seem to matter. The land hunted on in North Dakota is usually owned by farmers. We have to ask permission to hunt on private land. Usually the farmers are reasonable and for letting us hunt we give them a jar of maple syrup. I would suggest to anyone hunting on private land, to ask permission and give something to the owner in return. Since most fields are bean and corn fields, the farmers dont have much maple syrup because of very few maple trees.They are very thankful, and love when we give them the maple syrup. Ducks arent nec essarily a favorite of ours to eat, so as another act of thanks, we cut up the ducks breast and give it to the farmer. Usually the Gadwalls and the Northern Mallards will have the biggest breast meat. While the Teal have much smaller breast meat. If someone urgencyed to write a 20 page paper on the basics of duck hunting, I think it would be very achievable. As the reader can tell, there is much more beneath the surface than just shooting a duck and calling it good. experience about the sports and its regulations need to be known to succeed.I would highly recommend duck hunting to anyone, it is by far my favorite animal to hunt. If there is a region close to you that is swampy and vegetated, chances are it will be a good place for a duck to eat and become a target. In conclusion, I hope anyone who reads this can take in the consideration I have for the love of duck hunting and make it their love too. I want everyone to take what they learned and tell it to other people, so they to o can have an amazing hobby of duck hunting. Just remember, if having a good time and shooting ducks sound like fun, this is the sport for you

Starbucks and Types of Ownerships Essay Example for Free

Starbucks and Types of Ownerships EssayMost companies have different showcases of ownerships from being a sole possessor to having a partnership. Starbucks has a legal entity, distinct from any individual persons, with the power to own property and conduct business, as well known as a Corporation. From comme il faut a Corporation, Starbucks has setbacks, provided they also have benefits. Starbucks plays a big role in the growth of the United States and many other countries. The transportation options were made thinkable by rail dashs, commercial airplanes, and mass-produced cars and trucks. They had the ability to pull money by selling shares of stock to outside investors for example, when they licensed themselves out to Target or Barns and Noble. However, investors poop easily and quickly convert their stock into cash by selling it on the open market. Having an ownership like a Corporation piece of tail also make your corporate stocks look like an attractive investment, w hich butt increase the number of people and institutions willing to buy or invest their time? Corporations can use shares of their own stock to acquire other companies or find willing buyers for a corporate stock.Starbucks being a corporation has unlimited liability, but the various shareholders who own the corporation face limited liabilities? For example, as such(prenominal) as they put in or invest into that specific company, is as much as they potenti exclusivelyy have of losing. Alex Whitt, an Assistant Manager at a Starbucks located in Manteca said, I enjoy the fact that the company I move around for is a Corporation because no matter what store I choose to work at or get transferred to, wont have a transition Id really need to get used to. Meaning, because Starbucks is a Corporation, each individual store is ran the same in some way shape or form from creating the same find for each customer to knowing how to make each drink the same because each Starbucks carries the sam e type of products to produce the same taste in ever cup. Its always a question that comes up.What was the company like when it frontmost started? Well, a lot can be learned about finding out the history of your favorite store. For Starbucks, 3 men got together for the love of coffee and opened up the first Starbucks store in 1971. English teacher Jerry Baldwin, history teacher Zev Siegel, and writer Gordon Bowker opened the store (The McGraw-Hill Companies) in the touristy Pikes Place Market in Seattle (The McGraw-Hill Companies). They all were interested in fine coffee and exotic tea, which was what Starbucks established for. They came up with the Starbucks name in honor of Starbuck, the coffee-loving first mate in Herman Melvilles Moby diaphysis (The McGraw-Hill Companies). Including that it gave off a romantic feel of the stores name as well.The logo, which is a two-tailed mermaid with the stores name circling it, was designed by an workman friend. Starbucks was inspired by A lfred Peet who opened a small store known as Peets Coffee and Tea. In the 1980s, Siegel got burnout and eventually left the company to lease other interests. Baldwin took over day-by-day management for the company and was acting chief executive officer. And Bowker stayed involved with the company but was more involved with his advertising and design firm.In 1982, Howard Schultz took on his new responsibilities at Starbucks (The McGraw-Hill Companies). Prior to this, there were many meetings and interviews within a year with Baldwin and Bowker before they finally made a decision. The stone keep to grow and got ideas from pretty much anywhere which has led up to the Starbucks that we know today. Entrepreneurship the spirit of innovation, the initiative, and the willingness to take the risk involved in creating and operating a business. Courtland L. Bovee, 2011)This is hardly what Howard Schultz had in mind he once said I believe life is a series of near misses. A lot of what we as cribe to luck is not luck at all. Its seizing the day and accepting responsibility for your future. Its seeing what other people dont and engage that vision. (Ogden)His vision of creating a coffee house where people not only have a cup of coffee, a place where people interact a third home away from home as the own Schultz puts it.Imagination, passion, a clear vision are some of Schultz ingredients for success. From a poor boy life history on the poorest neighborhoods in New York to the owner of a multibillion company Schultz trained for success. (Ogden)He used the same principles as to when he was an athlete he never gave up rather he tackled the situation with an attitude of endurance and stayed focused to overcome any situation. Schultz had a vision of creating an Italian Cafe experience here in the United States. His vision led him to launch his own Italian cafe.This was the beginning of something big. He built a brand, by focusing on the total experience of the Starbucks cu stomer. Schultz has made people his priority by meeting employees expectations in return he has built a loyal more dedicated workforce, resulting in higher levels of customer service. Our mission statement about treating people with respect and dignity is not just words but a creed we bang by every day, says Schultz (Ogden) Another key element to his success was his ability of recognizing his strengths and weaknesses.He knew he wasnt going to do it all by himself instead he recruit others that share the same vision and values and that brought different strengths to the mix. Till this day is something he fosters and attributes to his success. Without these key elements Starbucks would not be the company that it is now. His entrepreneurial vision and innovative thinking has placed him among the top business entrepreneurs. ?

Are Video Games Good For Children Children And Young People Essay

Are pictorial matter Games Good For Children Children And Young People EssayFor that matter, are photo racyys good for adults. Has anyone ever seen the personal effects of prolonged exposure to video games and the effects it has on someones family or the community? As a father, I have dealt with b escapeball effects of video games first-class honours degree hand. There have been numerous studies and debates on the subject of video games and the effects, whether positive or negative, they have on children. Video games are not good for children because of the negative effects to a childs deportment and overall health.Violent tendenciesChildren that bring carmine orientated video games have dis tactical maneuvered violent tendencies toward others. There have been numerous studies and look into conducted, on violent video games played by children, which suggest that children whitethorn become more aggressive after playing (Harvard Mental Health Letter, 2010) those types of game s and the coating behind this reasoning, are three traits of the personality, which are high neuroticism, disagreeableness, and low levels of conscientiousness (Harvard Mental Health Letter, 2010). Playing violent orientated video games cause children to incite and think aggressively (Harvard Mental Health Letter, 2010). These conditions whitethorn cause children to commit violent acts or behavior.Violent BehaviorIn addition to increased aggression, children who play violent video games are associated with increased violent behavior (Souccar, 2012). Because of this behavior, there have been multiple despicable acts much(prenominal) as the Virginia Tech shootings where a grease-gun killed over thirty people in 2007(Lee, Finley, 2011). In 1999, another devastating act in Columbine, Colorado, two teenage gunmen entered a school with weapons, killed twelve students and a teacher, before taking their own lives (Belanger, Wagner, 2011). Eric Harris and Dylan Kiebold were frequent play ers and program contributors to a violent video game called Doom (Lee, Finley, 2011). Children or teens, that do not commit violent acts, whitethorn still display ghoulish behavior.Pathologic BehaviorChildren that play video games exhibit pathologic behavior. There are many warning signs of pathologic behavior, such as lying about or hiding how much time is spent playing or disobeying parental limits losing interest in sports and hobbies choosing the game over time with friends and continuing to play despite plummeting grades(Wagner, 2008). This is a very touchy subject in my household. My thirteen year old step-son has exhibited pathologic behavior because of video games. When the neighbors kids come to ask him to play outside, he refuses and has continued playing his games. His grades at school have suffered because he does not concentrate on doing his readying and worries more about playing video games. He has told a few lies, thrown tantrums, kicked walls and our washing machin e, and is constantly disrespectful to his siblings, my wife and myself. My step-son has also exhibits signs of video game addiction.Video Game AddictionsChildren with video game addictions, if left untreated, could have disastrous effects as adults. There are millions of people all over the human race who love to play video games, either on game systems or online social media, but that love for the video games turns into tragedy for those with video game addictions. fit to Lee and Finley (2011), a couple in Korea went to a local establishment to feed their video game addiction, only to return home over quintette hours later to find their four month old baby girl dead because she was left alone. Also according to Lee and Finley (2011), parents in Reno, Nevada were arrested after their irresistible impulse with video games caused them to neglect to feed their two young children.Increase of Video Game AddictionsThe increase of video games addictions has prompted the opening of clini cs in countries such as the Netherlands, linked States, China, and other countries around the world, to help combat the effects of video game addiction (Belanger, Wagner, 2011). Also stated, by Belanger and Wagner (2011), the Council on Science and Public Health belatedly proposed adding video gaming addiction to a list of formal disorders, such as drug addiction. Video game addictions and its symptoms mirror other addictions so closely, that it was virtually classified as an official psychiatric disorder (Lee, Finley, 2011) by the American Medical Association (AMA) in 2007. With all of the negative effects of video games, such as addictions, there are good video games children can play.Good Video GamesThere are many video games that are good for children. everywhere the past few years, there have been many advances in good video games and game systems, such as the Wii from Nintendo and the EyeToy Kinetic from Sony, which engage the players with the game (Barros, et al, 2012). I and my family have played games on both systems, The Wii system controller is held by the player which controls the actions of the avatar on the screen. The Kinetic system is similar, but the player controls the exploit of the avatar with his/her body movements through the use of a camera. One game that is used to induce physical activity, with both gaming systems, is a game called jump, Dance, Dance (Barros, et al, 2012). The players are actively involved in the games that they are playing and are increasing their heart rate and physical activity. These Exergames (Barros, et al, 2012) are promoting exercise and physical fitness. up to now though there are good video games, there are still other negative effects, such as inactivity from playing non-active games, which whitethorn induce childhood obesity.Childhood ObesityFor children that do not have access to those types of games, cant afford the games, or right dont care to play them, a great deal play the games that they hav e, for long periods of time, which leads to the lack of physical activity, and the onset of childhood obesity (Childhood Obesity, n.d.). A report, issued by the U.S. Department of Health Human Services, mentions a few reasons children may play video games for long periods of time. It may be the lack of parental control, being left alone by their parents for hours at a time, or just having to stay inside because of safety concerns (Childhood Obesity, n.d.). There is a growing concern, from parents such as myself, that children are becoming lazy from the lack of exercise because of video games. This lack of exercise contributes to weight gain and obesity. I have a personal connection with this subject because a member of my family was constantly playing video games, not getting any physical exercise, became a social outcast, and over a short period of time became obese.Video Games Are Not GoodVideo games are not good for children because some children exhibit too many pathologic beha viors and display violent tendencies because of video games. Children become addicted to video games which may carry over into their adulthood they may lose all sense of reality, and their addiction to video games may become so severe, that tragedies happen because of that addiction. For other children, they may become obese because of the lack of physical activity. There are an abundance of good video games for children to play, but as a parent, I have been a witness to most of these negative effects for over 10 years and I am not going to let my step-son or any of my children play video games excessively. I will control how much time is spent playing video games make sure that they take extended periods away from video games to get their homework completed and to get daily exercise.

Analytical Approaches in the Pharmaceutical Industry

uninflected Approaches in the Pharmaceutical IndustryMiracles do happen and chances of happening much(prenominal) events argon r atomic number 18. Scientific discoveries crap withal seen such miracles. The approach and efforts needed in scientific happenings are based on basic principles. The mode of application of these established principles differ from one stream to another(prenominal) stream of scientific disciplines. The principle of chemistry and physics are amalgamated to give rise to number of measuring devices. These devices are further restructured to suit application.Analytical chemistry can be defined as the science and art of determining the composition of materials in terms of their elements or compounds contained1 in it. Qualitative digest gives useful details from which functional groups, structural features, atomic species or molecular species. Quantitative synopsis gives numerical data in units i.e. percentage, parts per million, moles per liter and so forth In above two types of analysis, the required data is obtained by measuring a physical property which is characteristically cogitate to respective component of amour i.e. the analyte2. The most important aspect of analysis is quantitative analysis. The techniques of uninflected chemist are of vital importance to the medicine and pharmaceutical industries. Products are usually thickening organic compounds or mixtures. Drugs prepared for human consumption requires strict standards of product quality be established and maintained.In past, method actings of biological assay were often the unaccompanied measure of product activity available. With the advent of modern instrumentation, techniques of analyst became more than versatile and less time consuming, and quantitative analysis supplemented and sometimes replaced biological assay.In those instances where it is possible to establish a rigorous correlation between biological activity and chemical composition of product, analysis can be invaluable in controlling manufacturing operations as well as in determination of product purity and activity.It is noted that the fare and advancement of analytical chemistry depends to a greater extent upon an intelligent application of the fundamentals of physical chemistry and close relationship between physical and analytical chemistry.Recent rapid shape up in physical methods of analysis, in m both instances, resulted from pioneering investigations of scientists, principally physicists.In 1930 Willard recognized the demands being placed on analytical chemistry by rapid industrial progress. A parallel recognition of importance of analytical chemistry to industry occurred in Europe in same year.Churchill states that contribution of the analytical chemist to query program will be most effective if he is given the opportunity to participate while the program is being planned.In 1940s some(prenominal) direct reading quantitative spectrophotometers were reported. In thes e instruments the emitted spectral energy of certain chosen lines is transformed to a proportional electrical output by photomultiplier tubes. By suitable amplification and with appropriate preserve devices, percentages of the constituents present are automatically recorded. The outstanding advantage of such equipment is its ability to reduce the time requirement for playacting an analysis.New information made available by combining various tools of analytical chemist, has been described in several articles.The methods of analysis used to solve industrial problems whitethorn be classified as-Fully break offed, generally accepted methods of analysis.Generally accepted methods which are adapted to make them suitable for the problem.New methods which must be pauseed when available ones are not adequate.Industrial analysis is defined as the utilization of chemical and physical techniques for solving problems arising in industry.In some industrial processes it is desirable to obtain a very rapid or continuous analysis of a product or mixture. Considerable progress has been made in developing automatic method of analysis to fulfill this need. While it has not often been possible to automate entire procedures, from sampling to recording of results many examples of partly automated analytical operations can be cited.Factors pertinent to evaluation of analytical methods in each of these groups were discussed in the present section.A method of analysis is standard or accepted only in the sense that a number of analysts have judged it to be adequate for obtaining certain analytical information.Ideally, analyst views the standard method as a best approach rather than an obvious solution. If satisfactory results are obtained the method can be apply to the type under consideration with some assurance that the experimental procedure is not at fault. The analyst himself should perform this part of work even if proximo measurements will be carried out by technicians or laboratory assistant. Only by performing the manipulation and observing the reaction can the analyst forming good acquainted with the details of an analytical procedure.The advisable method is when it appears to give satisfactory results, include consideration of interfering elements or compounds and determination of blank. While interferences which prevent a method from working properly are readily detected, those which produce a constant error in the analytical result are much more insidious and seldom apparent. Determination of a blank eliminates possible source of constant errors, such as contaminants in reagents and uncorrected background in slavish measurements.In many standard methods the design and dimensions of the equipment are critical, particularly when properties of material rather than its composition is being studied.Many modification of an analytical method are possible and each problem or sample dictates the changes required to make the method effective.In some me thods modification involves change in equipment or technique. For example, legion(predicate) spectrographic procedures have been developed for analyzing the metallic contaminants or additives in lubricating oils.Methods, which fail or suffer loss in sensitivity when certain interferences are present, may sometimes, need to be modified by introducing an additional step in the procedure which eliminates or deactivates the interfering element.Once a procedure has been adapted to a particular problem it may be evaluated in the same manner as a standard method. The usual precautions related to proper manipulation and standardizations, avoiding befoulment and blank determinations must be observed.When problem is confronted which cannot be solved with established methods of analysis, it becomes necessary for analyst to create and develop new analytical procedures. This situation arises when any or all of the following factors are in effect.The contentedness sought has not previously bee n unconquerable, when no methods are now available for all elements.The substance sought is a component of a mixture not previously analyzed. Any other element or compound present in a mixture may invalidate established methods of analysis by interference effects. Sometimes the component producing the interferences can be eliminated and a modified form of the original procedure can be used, as already described.Higher order of sensitivity is required when component sought is present in small standard (mg). A method capable of analyzing in desired concentration range must be developed.Problems arising in industry are complicated by sample limitations. Often the sample is available in very small amounts and special techniques are required for gaining maximum information from a minimum quantity of material. abbreviation must be non-destructive. At times it is required that the sample remain unaltered by the analytical procedure. For example compositional information on an high-pric ed finished product is required, a non-destructive analytical method.Speed or time is critical requirement when conventional methods cannot complete an analysis within a appointed time requirement, faster methods must be developed.Analytical Chemistry importance in different scientific areasImportance of analytical chemistry in related scientific areas can be demonstrated by considering analytical chemistrys impact on clinical analysis, and in pharmaceutical research and in quality control.Sensitive chemical and instrumental tests were advised in order to detect abnormal and normal components of body fluids.Blood and urine samples are determined for percentage of glucose, urea, nitrogen, protein, sodium, potassium, calcium, uric acid etc.Similarly, the quality of manufactured do drugs in tablets, solution and emulsion form must be carefully controlled in pharmaceutical industry, otherwise the drug can itself affect the therapeutic value. In other pharmaceutical studies, it is impor tant to establish properties and therapeutic value of a drug before the drug is approved and made available to the public.Analytical TechniquesFew of medicinal products were still being analyzed by time-tested procedures of gravimetric and also titrimetric procedures. A broad(a) diversity in different type of analytical techniques has been characteristic of assay methods for pharmaceutical products. Different analytical techniques were been employed for estimation of wide variety of components in the formulation-Titrimetric and gravimetric methodColorimetric and UV spectrophotometric methodPaper chromatographyPreparative thin layer chromatographyColumn chromatographyIon-exchange chromatographyFlame photometry and atomic absorption spectrometry.Variables in Quantitative AnalysisInhomogeneity of the medicamentSampling errorPreparation of samples such as extractionPrecision, accuracy and ruggedness of the method stochastic error including that of the operator.Newer Analytical Techniqu esAs technology is developing, a number of new drugs are launched in the market and it is essential to develop new methods of analysis.It is necessary to do ifNo analytical methods are available for a drug in official books such as pharmacopoeias.No literature reveals methods for estimation of drugs.Analytical method available only for single drug in a combined form of drug.No method reported for the estimation in biological fluids. unavoidableness OF ANALYTICAL APPROACHES IN PHARMACEUTICAL INDUSTRYThe pharmaceutical industry has always had in place a series of process controls which assures the integrity of the end product. A simple way of looking at it is that the Food Drugs Act Regulations are merely an auditing mechanism to quantify that industry has sufficient process controls and documented procedures in place to ensure they are in complete control of every aspect related to drug manufacturing,There are in essence, three pillars to drug manufacturing and distribution1. Quali ty Assurance (QA)2. Good Manufacturing Practices (GMP)3. Quality Control (QC)Quality Assurance is ensuring that you get what you pay for. It is the insurance policy for the manufacturer. As a plan overview, the GMPs are part of Quality Assurance and ensure that drugs are produced consistently and are controlled at each and every step. QC is a part of Good Manufacturing Practices and is trusty for(p) for sampling and also for testing. It examines and ensures that all aspects of product from raw materials and integrity of the product itself to the packaging materials and insert, meet their specifications. It encompasses testing of the end product and all of its primary ingredients. QA covers documentation of all of the procedures that have behaven place from start to finish of entire process. This, in combination with QCs sampling and testing, allows QA to ensure products integrity, purity and potency have not been compromised and it has satisfied all requirements. When QA is com pleted and satisfactory, the terminal step is permitted allowing a product to be released for sale to the consumer.But, their job doesnt stop here. Since Quality Assurance is responsible for assuring that final product is meeting quality, consistency and integrity for its intended use, it must also account for when the product leaves the manufacturing site. Thus, QA is also responsible for ensuring that appropriate arrangements have been made with distributors and warehouses to guarantee that the product is handled, stored and shipped in such a way that its quality is maintained for the duration of its approved shelf life.The overall time required for development of a pharmaceutical from Discovery Research through to the Regulatory Review Phase. There is clear evidence that this can in some cases take upwards of 15 years with costs reaching into millions of dollars. With this level of Research and Development investment, the industry has no intention of allowing a breakdown in fina l stages of manufacturing and distribution process. Therefore, before a product actually reaches market, QA involvement is also the key in the registration dossier preparation. A portion of this dossier contains a Master turnout Document (MPD) which outlines exactly how the product will be manufactured. Within this MPD, a manufacturer defines clear specifications for all raw materials, packaging materials, in-process and finished product along with the sampling procedures and also Standard Operating Procedures (SOPs) related to critical processing. The issuing of a Notice of Compliance and a Drug Identification Number are contingent on a complete and acceptable Master Production Document.Then manufacturing license aimers are also responsible for conducting an annual self-inspection and documenting their procedures and processes are in compliance with the requirements of the GMPs.If the manufactured product is stored in bottles (syrups), fabricating, packaging/labeling, importation , distribution, wholesale (Schedule C, D, F or G products) or testing of pharmaceutical products must first hold an Establishment License issued by Government.PRESENT STUDYDevelopment of new drugs, drug manufacturing is dependent on drug analysis. Pharmaceutical companies depend upon drug analysis quantitatively to conform that the raw materials used, in-process compounds and final products manufactured were meeting the required specifications. New drug formulations and new drugs were introduced into the market at increased pace compared to antecedent days, as the technology is developed. These formulations and drugs were either new chemical entities or partial structural modifications of existing drugs or new dosage forms. Frequently, it happens that the new drugs inclusion in pharmacopoeias will be delayed because of several reasons. Hence these standards or the analytical methods for these drugs may not be available in pharmacopoeias. Hence it is essential to develop new methods of analysis for these drugs. Based on this, few combinations were selected for the present studies which were currently marketed from Anti Hypertensives17-22, Anti HIV23-35 and Non Steroidal Anti Inflammatory Drugs36-47.Amlodipine BesylateTelmisartanLamivudineZidovudineThiocolchicosideEtoricoxib writings survey was performed extensively and it was found that spectrophotometric methods were reported and also HPLC methods were reported for the determination of these drugs from their biological fluids. However, there were no reports found for their quantitation by HPLC methods from their formulations. Hence it is essential to develop newer rapid analytical methods3-16 on HPLC.

Biography of Dorothy Johnson Vaughan

Biography of Dorothy Johnson VaughanAbstractThis research paper explores the life and journey of how Dorothy Johnson Vaughan became a female African-American mathematician who worked for the National informative Committee for Aeronautics(NACA) in 1940-1970. A woman who excelled at the facility in many ways despite the fact that she was an African-American and a woman in the era of segregation between race and gender. Her excellence along with other African-Americans such as Mary Jackson and Katherine Johnson are the reason for the come acrossments in the lieu Race and bringing confidence back to Americas space course. She along with these two women are subject in the 2016 film cloak-and-dagger Figures.Dorothy Johnson Vaughan was a mathematics instructor in the early 1940s. As an African-American and a woman, this was a significant role in American history considering both parts were put come out in this era. She was the first of her kind to be promoted as a supervisor in NACAs (National Advisory Committee for Aeronautics) program, which is now called NASA. She became one of the most memorable figures along with other female African-American mathematicians who are the subject to a 2016 film Hidden Figures.On September 20,1910, Dorothy was born in Kansas City, Missouri however, she also was raised(a) in Morgantown, West Virginia. Her parents were Leonard and Anne Johnson. In 1925, she graduated from Beechurst High school and went straight to Wilberforce University in Ohio where she received a Bachelor of Science degree in mathematics. after(prenominal) college, she was accepted a position as a math teacher at Robert Russa Moton High School in Farmville, Virginia. In 1932, she married Howard Vaughan whom she had six children with. Their name areAnn, Maida, Leonard, Kenneth, Michael and Donald (Biography).This was her life for eleven years until she and her family moved to Newport News, Virginia to be employed as a mathematician at the National Advisory Committee for Aeronautics. This was placed at the Langley history Aeronautical Laboratory in Hampton, Virginia where she thought would be just a temporary position. She was assigned to a segregated group that consisted of all African-Americans, called West nation Computers (Shetterly). This is where she also met Mary Jackson and Katherine Johnson (the other subjects to the film Hidden Figures). She underwent working beneath the conditions of segregation with these women and many other African-Americans.Dorothy was appointed acting supervisor of the program in 1949, after the death of her manager and thus become the first African American woman to be promoted in the agency. It took two years for her to achieve permanent status in that position. After NACA became NASA (National Aeronautics and Space Administration) in 1958, she continued her work there. NASA, at the time, worked as a part in resultant racial segregation at the facility. She also had to prepare for the introduction of machine computers in the early 1960s by teaching herself and her staff the programming actors line of FORTRAN (Melfi).In the last decade of her employment with NASA, she worked with Mary and Katherine on the launch of astronaut John Glenn into orbit, which brought confidence back to Americas space program. She remained at NACA for twenty-eight years until such time as her retirement in 1971 at age 60. Dorothy died of natural causes at the age of ninety-eight on November 10, 2008, in her hometown of Hampton, Virginia (Biography).ReferencesBiography.com Editiors. (2016, November 14). Dorothy Johnson Vaughan. Retrieved fromhttp//www.biography.com/people/dorothy-johnson-vaughan-111416Melfi, T. (Director). (2016). Hidden Figures Motion picture. USA Fox 2000 Pictures, CherniEntertainment, Levantine Films,TSG Entertainment.Shetterly, M. L. (2016, December 1). Dorothy Vaughan Biography NASA. Retrieved fromhttps//www.nasa.gov/content/dorothy-vaughan-biography

societhf Seclusion from Society :: Adventures Huckleberry Huck Finn Essays

Huckleberry Finn Seclusion from Society     Imagine the amount of freedom one feels as they drift down a river voluntarily stranded on a raft. The thought of it is relaxing to the mind, but actually experiencing it for yourself is a whole new happening. The freedom, no worries, no sounds but the noise of the river water rushing and the sounds of gravy holder horns off in the distance. In Mark pas de deuxs novel The Adventures of Huckleberry Finn, the author effectively symbolizes the river as a place outside of society. In the novel, The Adventures of Huckleberry Finn duet uses the river as an carry from society for the characters Huck and Jim. Twain is showing examples of his own life through the character Huck. The reason for saying this is that Twain had grown up amongst many rivers in his life time, including a New York town named Riverdale which is now a part of the Bronx, New York Citys northernmost borough, Riverdale was a separate residential communi ty when Mark Twain rented a house there in 1901.(Rasmussen, 391) Twain loved the water so much that he piloted many steamboats on the Mississippi River. The last steamboat on which Twain worked as a pilot was the Alonzo Child. The Alonzo Child was a 493-ton side-wheeler, the Child was built in Jeffersonville, Indiana for the Missouri river trade around 1856 (Rasmussen, 8). This is an example of how Twain lived by many rivers and how Twain used the river to get away from society.   In Twains novel the character Boggs shows an excellent example of someone who is lost and uses seclusion as an escape from society. In chapter twenty-one, Huck is idling in the scruffy village of Bricksville, when Boggs charges in on a horse during his monthly drunk. A red face man in his in his fifties. Boggs rides about wildly hurling insults and threats proclaiming that he has come to kill Colonel Sherburn.(Rasmussen, 39) This shows that people dont give him as much respect as he woul d like because when he gets drunk he acts very irresponsible and he is a bad role model. There for Boggs secludes himself to his home to hide his embarrassment.

Douglas MacArthur Essay -- essays research papers

Douglas MacArthur was a US soldier, born in Little Rock, Arkansas, USA. The son of a Union army hero during the Civil struggle (they are the only father and son to win the Congressional Medal of Honor) and a mother ambitious for his success, he trained at westernmost particular (1903), rose steadily in the army, and demonstrated his bravado on a secret mission to Mexico (1914). In World War 1 he commanded a brigade in combat in France (1918), where he earned a reputation for bravery (wounded three times) as well as foppery - he carried a muffler and a riding crop into the line, but not a helmet or a gas mask. After serving as the superintendent of West Point (191922), he completed his second tour of duty in the Philippines. Appointed army chief-of-staff in 1930 (the youngest ever), he offended liberal-...